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KMID : 0191120030180020267
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Journal of Korean Medical Science
2003 Volume.18 No. 2 p.267 ~ p.271
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Metabolic Changes after Revascularization in a Patient with Innominate Artery Occlusion by Localized in vivo Proton Magnetic Resonance Spectroscopy
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Yong Pil Cho/Yong Pil Cho
Jung Hee Lee*/Geun Eun Kim†
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Abstract
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Localized in vivo proton magnetic resonance spectroscopy (1H-MRS) has been used to measure the metabolic status of the human brain in a non-invasive manner; thus, it is often called "a non-invasive biochemical assay". MRS is more sensitive than magnetic resonance imaging (MRI) in detecting ischemic damage by measuring the metabolic changes that occur prior to the anatomic changes. We report a patient who presented with innominate artery occlusion and symptoms of posterior circulation insufficiency and showed favorable metabolic changes by 1H-MRS after revascularization. He showed no visible lesion in brain MRI, but in 1H-MRS, decreased N-acetylaspartate (NAA) signal was noted in a resting state. After revascularization, both symptomatic improvement and recovery of NAA signal were observed. 1H-MRS may provide valuable clinical information in diagnosis and management of cerebral hypoperfusion at a much earlier stage prior to the anatomic changes.
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KEYWORD
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Magnetic Resonance Spectroscopy, Brachiocephalic trunk, Arterial Occlusive Diseases, Reperfusion,
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